2024-03-29T17:45:50Z
https://adjalexu.journals.ekb.eg/?_action=export&rf=summon&issue=22329
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
THE EFFECTIVENESS OF MELATONIN IN REDUCING PAIN RESULTING FROM RADIATION INDUCED ORAL MUCOSITIS: A RANDOMIZED CLINICAL TRIAL
Hossam
Elsabbagh
Eglal
Moussa
Sabah
Mahmoud
Rasha
Elsaka
BACKGROUND: Oral mucositis is a common side effect of anticancer radiotherapy causing severe ulceration of the mucosal tissues. Recently, melatonin supplements have been proposed as a new therapeutic modality for oral mucositis due to its antioxidant effects, anti-inflammatory, and anti-cancer properties.OBJECTIVES: evaluation of the effectiveness of melatonin in reducing pain resulting from radiation induced oral mucositisMATERIALS AND METHODS: Forty patients were randomly assigned to receive either: conventional treatment of oral mucositis, or 20 mg melatonin treatment in combination with the conventional treatment before irradiation, and for six weeks. All patients were evaluated for pain resulting from oral mucositis at three and six weeks after the start of radiotherapy.RESULTS: Oral mucositis patients in the melatonin group have experienced significantly lower pain scores oral mucositis compared to the control group.CONCLUSION: Adjuvant melatonin reduced the pain of oral mucositis, and the amount of analgesics used for pain treatment.
Melatonin
Oral mucositis
Radiotherapy
2021
04
01
1
5
https://adjalexu.journals.ekb.eg/article_144849_8cc63b445ed2659d1acd1e4added1d93.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
EVALUATION OF CHITOSAN/HYDROXYAPATITE SCAFFOLD ON THE HEALING OF OSSEOUS DEFECTS IN JAW BONES (CLINICAL STUDY)
Dina
Abd EL Hafez
Tarek
Ali
Adham
El Ashwah
INTRODUCTION: The repair and replacement of injured or defective bone is a critical problem in orthopedic treatment. Bone defects in the maxillofacial region are considered a serious health problem. The correct restoration of architecture and function of tissues of this important anatomical region is mandatory. A variety of methods are employed for treating such defects, however, each of the strategies has its own drawbacks. Significant development has been achieved with combining bioceramics and biopolymers. Chitosan/ nano-Hydroxyapatite (CH/nHA) has recently emerged a new strategy for promoting bone regeneration and enhancement of bone healing and remodeling. This composite has increased cell adhesion, cell proliferation, mechanical strength, alkaline phosphatase activity, protein adsorption, type I collagen production as well as expression of other osteogenic differentiation markers.OBJECTIVES: The aim of the present study is to assess the effectiveness of using Chitosan/ nano-Hydroxyapatite composite on healing and regeneration of bony defects of the jaws radiograhicaly by the aid of Cone beam computed tomography.METHODOLOGY: This study was performed on 14 patients having bone defects in their maxilla or mandible due to cysts or tumors. Patients were divided into two groups; test group in which patients had removal of bone lesion leaving bone defects treated with Chitosan/nano-Hydroxyapatite, and control group in which bone defects were left to heal spontaneously. Bone defects were examined radiographically using Cone beam computed tomography.RESULTS: A significant increase in bone density in bone defects treated with Chitosan/nano-hydroxyapatite, as well as significant decrease in bone defect size.
Chitosan
nano-hydroxyapatite
Bone defect
bone regeneration
2021
04
01
6
14
https://adjalexu.journals.ekb.eg/article_144906_163264ffad4d42c60bfc562a3ac293b8.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
CORTICAL TENTING TECHNIQUE FOR VERTICAL AUGMENTATION OF ATROPHIC POSTERIOR PART OF THE MANDIBLE (CLINICAL TRIAL)
John
Hares
Sherif
Mohamed
Marwa
Noureldin
INTRODUCTION: The progressive decrease in the alveolar bone volume after tooth loss impedes the use of dental implants for rehabilitation of edentulous regions. This fact is of utmost significance in the posterior areas of mandible, where the presence of inferior alveolar nerve further complicates the proper insertion of dental implants. Considering the drawbacks of the non-reconstructive treatment options, restoring deficits of alveolar ridges by reconstructive procedures might still be more practicable, despite the invasiveness. The majority of reconstructive techniques involve a process of bone grafting and vertical ridge augmentation. Cortical tenting technique is used for vertical ridge augmentation and can achieve a good degree of success.OBJECTIVES: To evaluate the effectiveness of cortical tenting technique in vertical ridge augmentation of atrophic posterior mandibles.METHODS: The study was made on ten patients with atrophic posterior part of the mandible. In each one of them, the atrophic alveolar ridge will be treated with cortical tenting technique. Bone height over the mandibular canal was measured on Standardized CBCT scans taken preoperatively (base line), and 1 week and 4 months postoperatively and bone density was measured at grafted area 4 months postoperatively.RESULTS: The average final bone gain was 4.540 mm at the end of follow up period with 1.700 mm average of graft resorption. Estimated bone density was measured also at grafted area 4 months after surgery with a mean value of 398.59 voxel value (VV).CONCLUSION: The use of cortical block graft taken from the ramus of the mandible to augment vertical bone defect in the posterior of the mandible has significant success rates.
Vertical augmentation
Cortical tenting
Atrophic mandible
piezosurgery
2021
04
01
15
22
https://adjalexu.journals.ekb.eg/article_144851_6b710ca3c26f65676594637b9696ef26.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
ACCURACY OF TOOTH GUIDED IMMEDIATE IMPLANT PLACEMENT AT MOLAR REGION (CLINICAL TRIAL)
Abdelrhman
Abdelazim
Samraa
Elsheikh
Hala
Ragab
INTRODUCTION: The concept of immediate implant placement has become popular due to reduced trauma and reduced overall treatment time. Removal of molar teeth provides a challenging and intriguing dilemma due to multiple root morphology. In cases of extraction and immediate placement of implants in the molar region, removal of the inter-radicular septum should be avoided to attain initial implant stability at the time of placement, and prevent slipping of the implant into the extraction socket. Following this technique prevents the slippage of the implant and allows the implant to be guided into the inter-radicular septum.OBJECTIVES: To assess the accuracy of implant placement using the remaining roots of multi-radicular mandibular molars, evaluate bone density around implants and implant stability in fresh extracted site.MATERIALS AND METHODS: A prospective study was done on 10 patients with badly destructed mandibular molars. The technique of implant insertion consisted of a progressive preparation of the implant site using the anatomy of the root of the multi-radicular mandibular molars to be extracted as a reference and as an aid to engage the inter-radicular septum. Implant stability was evaluated using Osstell; Radiographic evaluation was done by Cone Beam Computed Tomography.RESULTS: Nine out of ten implants were functioning successfully along the evaluation period, while one implant failed 4 weeks after insertion and was removed. Clinically, implants stability was assessed using Osstell. All implants showed increase in ISQ value after 3 months. Radiographically, immediate postoperative CBCT was carried out which showed implants placed in ideal position. After 6 months, CBCT showed increase in bone density around implants compared to the immediate postoperative CBCT.CONCLUSIONS: Tooth guided immediate implant placement at molar region is a novel technique for easy and safe implant insertion.
Guided surgery
Immediate placement
implants bed preparation
2021
04
01
23
28
https://adjalexu.journals.ekb.eg/article_144837_5afe76c1cb51a89551717db185638756.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
EVALUATION OF "TENT-POLE" GRAFTING TECHNIQUE FOR RECONSTRUCTION OF MANDIBULAR RIDGE VERTICAL DEFECTS (CLINICAL AND RADIOGRAPHIC STUDY)
Asmaa
Abd Elfattah
Abd El Aziz
Khalil
Lydia
Melek
regeneration after loss of the adequate bone height. Numerous techniques have been mentioned for reconstruction of the atrophic mandibular ridge. Tenting of the soft tissue matrix allow maintaining space for the graft material for vertical ridge augmentation.OBJECTIVES: The aim of this study is to evaluate clinically and radiographically the efficiency of "Tent- Pole" grafting using titanium mini-screws with guided bone regeneration for augmentation of mandibular ridge vertical defects.MATERIALS AND METHODS: Twelve patients with posterior mandibular defects were treated with guided bone regeneration around titanium screws that tent out the soft tissue matrix with an age range of 43 and 60 years. They were of both sexes (4 males and 8 females). Osteosynthesis mini-screws were fixed on the alveolar ridge with an average of 2-3 mm of their length exposed, alloplastic material surrounded the screws completely and a resorbable membrane is used for the guided bone regeneration.RESULTS: The mean bone height value after six months was found to be statistically significant with the mean bone height value preoperatively and immediate post operative (p < 0.001). Also, there was statistically significant difference in the mean bone density between the six months post operative and immediate post operative values (p < 0.001).CONCLUSION: From the results of this study, the screw tent -pole grafting technique with guided bone regeneration is a technique of high reliability in restoring mandibular vertical bone loss.
Tent-pole
guided bone regeneration (GBR)
Mandibular defect
2021
04
01
29
35
https://adjalexu.journals.ekb.eg/article_144845_6a026e147bc40b6b7bc30e7539129651.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
COMPARISON BETWEEN THE LINGUALLY BASED AND THE BUCCALLY BASED TRIANGULAR FLAP DESIGN IN THE SURGICAL REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS (CLINICAL TRIAL)
Nesma
Said
Saeeda
Osman
Ahmed
Sweedan
INTRODUCTION: Removal of wisdom teeth could be challenging owning to limited accessibility, the tooth’s structural location and probable nerve damage especially to the inferior alveolar nerve and the lingual nerve.OBJECTIVES: The primary goal of this study is to make a comparison between the lingually based triangular flap and the buccally based triangular flap in terms of post-operative healing and complications.METHODS: 20 patients between the age of 21 and 30 years were randomly selected for mandibular third molar removal from clinic of the Oral and Maxillofacial Department, Faculty of Dentistry, Alexandria University. They were divided into two groups the study group (n=10) was operated using the lingually based triangular flap design and the control group (n=10) was operated using the buccally based triangular flap design. The patients were recalled on the 2nd, 7th and 14th days postoperatively in order to evaluate postoperative pain ,swelling ,wound dehiscence , the incidence of dry socket formation and lingual nerve injury.RESULTS: The lingually based triangular flap showed inferior levels of pain and was statistically significant in the 3rd and 7th day postoperatively . The lingually based triangular flap design showed less amount of facial swelling and lower incidence of wound dehiscence, dry socket formation and lingual nerve injury but the difference between the groups was all statistically insignificant.CONCLUSION: Lingually based triangular flap design revealed better postoperative healing than buccally based triangular flap design.
Lingual Triangular Flap
Buccal Triangular
Impaction
mandibular molar
2021
04
01
36
42
https://adjalexu.journals.ekb.eg/article_144852_e7ccc7676023e4e997389d13770d15d1.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
MACRO VERSUS MICRO THREAD DESIGN IMPLANT AND THEIR EFFECT ON THE STABILITY
Ahmed
Saleh
Ahmed
El- Mahallawy
Hala
Ragab
Introduction:Dental implants are considered stable tools for replacing missing teeth, achieving long-term success rates above 90 percent, and their use in dental practice has become normal. One of the reasons to this success is the primary reliability of an implant. Implant design is one of the main factors that play a role in stability. Objectives: The purpose of this study was to compare the role of the Macro thread design and the Micro thread design on implant stability through the use of the Resonance Frequency Analysis (RFA). Materials and Methods: The study was carried out on 6 patients, each of these patients has missing teeth on each side of posterior area in the lower jaw. All the right sides received Micro thread design implant (dentium implant,) and the left side received Macro thread design implant (Megagen AnyRidge). After dental implants were placed in their sites, the stability was measured by using the Resonance Frequency Analysis (RFA) to assess the stability of the two types of implants at three times periods: At the time of placing the implant, 3 months and 6 months. Results: The mean implant Stability value for Group A was 70.57±5.74 immediately post-operatively, on the 3 month to 77.14±6.74 and reach 84.29±6.02 on the 6 month, for Group B was 63.29±6.58 immediately post-operatively, on the 3 month 70.57 ± 4.69 and on the 6 month 77.14±4.53. The mean bone density values for Group A at 3 months was 481.98± 51.78 and at 6th month was 504.28± 47.50, in Group B the 3 months was 439.54±70.49 and at 6th month was 463.83± 74.44. Conclusion: The Micro thread design implants shows higher stability than Macro thread design.
Osseo integration
Implant design
Dentium implant
Megagen AnyRidge
Resonance Frequency designs available Analysis
CBCT
2021
04
01
43
50
https://adjalexu.journals.ekb.eg/article_144843_11f973cef59958e1d24b53df34d30b9c.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
ULTRASOUND GUIDED CLOSED REDUCTION VERSUS OPEN REDUCTION OF ZYGOMATIC ARCH IN ZYGOMATICOMAXILLARY FRACTURES
Tasneem
Amer
Ahmed
sharara
Nevien
Mohamed
Riham
El Dibany
mohamed
el shafei
Introduction: trauma of the zygomaticomaxillary complex (ZMC) has profound functional as well as aesthetic implications. Treatment of ZMC fractures remains one of the most controversial issues in maxillofacial trauma with regard to the classification, diagnosis, surgical approach and treatment.Precise management of the ZMC fractures needs accurate diagnosis, accessible exposure, and precise rigid fixation Objectives: To compare between ultrasound guided closed reduction and open reduction of zygomatic arch in cases of ZMC fracture. Materials and methods: This study was conducted on a sample of twenty patients who had fracture repair of ZMC. Ten of them (study group) were treated via direct peri-orbital approach with the use of intra-operative ultrasound to guide zygomatic arch reduction. While the other ten patients (control group) via coronal approach with open reduction of zygomatic arch. Postoperative patient evaluation was performed with specific attention paid towards zygomatic arch reduction, nerve function, wound healing, and postoperative ocular complications. Results: Radiographic follow up showed no statistical significant difference between normal side and reduced side of zygomatic arch which reflect satisfactory arch reduction among both groups. Conclusion: From the results of this study it was concluded that ultrasonography is an effective method for guiding zygomatic arch reduction with other minimal incisions in cases of ZMC fracture. On the other hand, coronal incisions have advantages of giving excellent access to ZMC fracture with direct reduction of zygomatic arch but with considerable disadvantages.
ZMC fractures
Ultrasound guided reduction
Coronal incisions
2021
04
01
51
57
https://adjalexu.journals.ekb.eg/article_127964_87f1f255db1762a7487349c743912c4a.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
PROSPECTIVE RANDOMIZED STUDY BETWEEN ARTHROCENTESIS AND OPERATIVE ARTHROSCOPY IN THE MANAGEMENT OF TEMPOROMANDIBULAR JOINT INTERNAL DERANGEMENT
Aly
Atteya
Mohamed
Warda
Mohamed
Fata
Ahmed
Medra
Florencio
Gil
Introduction: Temporomandibular disorders (TMDs) are common conditions and internal derangement is the most common among them. Different methods have been suggested for treatment , beginning with conservative approaches ending with surgery. Nowadays, arthrocentesis and arthroscopy have decreased the need of the more complex surgical procedures. Despite such advancements, there is deficiency in the literature regarding prospective, randomized, clinical studies supporting either both of them. In doing the necessary studies, and comparing the results, it will be essential to develop a standardized criteria for patient selection and treatment options that can be used by all investigators. Objectives: To compare between arthrocentesis and operative arthroscopy in the management of patients with internal derangement of temporomandibular joint stage II and III Wilkes. Materials and Methods: a prospective study was done on 40 patients with temporomandibular joint internal derangement and were divided into 2 groups, 20 patients were treated with arthrocentesis and 20 patients were treated with operative arthroscopy. Results: The pain score was significantly lower in operative arthroscopy. The mouth opening was significantly higher in the operative arthroscopy. Conclusions: Operative arthroscopy is better than arthrocentesis as regards the postoperative pain and mouth opening.
TMJ
TMJ Arthroscopy
Arthroscopy
Arthrocentesis
internal derangement
2021
04
01
58
65
https://adjalexu.journals.ekb.eg/article_128033_32fce0c8e2de238b6cf84ceb59cb1d07.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
DENTAL STEM CELLS (CONCEPTS AND APPLICATIONS)
Ahmed
Hussein
Zeinab
Darwish
Hanaa
Raslan
Mahmoud
Attia
Hend
Abdel-Hamid
Stem cells constitute the source of differentiated cells for the generation of tissues during development, as well as for regeneration of tissues that are diseased or injured postnatally. The stem cell research has grown exponentially to improve the life of patients with conditions that span from Alzheimer’s disease, cardiac ischemia to bone or tooth loss. In dentistry, stem cell biology and tissue engineering are of great interest since they may provide an innovative for generation of clinical material and/or tissue regeneration. Mesenchymal stem cells were demonstrated in dental tissues, including dental pulp, periodontal ligament, dental papilla, and dental follicle. These stem cells can be isolated and grown under defined tissue culture conditions and are potential cells for use in tissue engineering including dental tissue, nerves and bone regeneration under appropriate conditions. This review was performed to study the concepts of stem cells and the most recent application of dental stem cells.
stem cells
Dental stem cells
Pluripotent
Multipotent
2021
04
01
66
71
https://adjalexu.journals.ekb.eg/article_88450_752a41083d98192a3ace3191f3d942f3.pdf
Alexandria Dental Journal
1110-015X
1110-015X
2021
46
Issue 1
QUANTITATIVE ASSESSMENT OF TUMOR ASSOCIATED TISSUE EOSINOPHILIA IN ORAL SQUAMOUS CELL CARCINOMA (CLINICOPATHOLOGICAL STUDY).
Mohamed
Deban
Fatma
El Didi
Omneya
Ramadan
ABSTRACT INTRODUCTION: Oral Squamous cell carcinoma (OSCC) is the 11th most common cancer worldwide. Tumor stroma consists of various inflammatory cells resulting from the host-response to tumor cell. Increased tissue eosinophil levels have been reported in various malignancies including OSCC. Tissue eosinophilia is a regular finding in allergic and parasitic disorders, but their role still needs to be evaluated in OSCCs. Specific stains as Congo red is a useful diagnostic means for detecting eosinophils owing to their distinctive quality to combine with eosinophils. OBJECTIVES: was to evaluate and compare eosinophilic infiltration in both metastatic and non-metastatic oral squamous cell carcinoma using Congo red stain and their correlation to the tumor grade. MATERIAL AND METHODS: Fifty histopathologically proven OSCC were included in this study and were allocated into 2 groups where the first group included 25 cases of metastatic OSCC and the remaining 25 cases are non-metastatic OSCC. Congo red was utilized as a distinct stain for eosinophils. Each specimen slide was inspected under high power in 10 successive microscopic fields to count eosinophils. RESULTS: the eosinophilic count was found to be higher in non-metastatic tumors when compared to metastatic tumors. CONCLUSION: eosinophilic count is a strong indicator of the stage of the tumor and its differentiation. KEY WORDS: Carcinoma, Congo Red, Eosinophils, Eosinophilia, Mouth Neoplasms, Squamous Cell.
carcinoma
Congo red
Eosinophils
Mouth Neoplasms
Squamous Cell
2021
04
01
72
77
https://adjalexu.journals.ekb.eg/article_127951_c75debccdd5e85aa46974350ed7d50ed.pdf