Tageldin, M., Ismail, H., Mowafy, M., El Sawa, A. (2021). EFFECT OF LOCAL ADMINISTRATION OF HYALURONIC ACID ON ORTHODONTIC TOOTH MOVEMENT IN A RABBIT MODEL. Alexandria Dental Journal, 46(Issue 1), 144-148. doi: 10.21608/adjalexu.2020.29374.1064
Mostafa A. Tageldin; Hanan A. Ismail; Mohamed I. Mowafy; Afaf A. El Sawa. "EFFECT OF LOCAL ADMINISTRATION OF HYALURONIC ACID ON ORTHODONTIC TOOTH MOVEMENT IN A RABBIT MODEL". Alexandria Dental Journal, 46, Issue 1, 2021, 144-148. doi: 10.21608/adjalexu.2020.29374.1064
Tageldin, M., Ismail, H., Mowafy, M., El Sawa, A. (2021). 'EFFECT OF LOCAL ADMINISTRATION OF HYALURONIC ACID ON ORTHODONTIC TOOTH MOVEMENT IN A RABBIT MODEL', Alexandria Dental Journal, 46(Issue 1), pp. 144-148. doi: 10.21608/adjalexu.2020.29374.1064
Tageldin, M., Ismail, H., Mowafy, M., El Sawa, A. EFFECT OF LOCAL ADMINISTRATION OF HYALURONIC ACID ON ORTHODONTIC TOOTH MOVEMENT IN A RABBIT MODEL. Alexandria Dental Journal, 2021; 46(Issue 1): 144-148. doi: 10.21608/adjalexu.2020.29374.1064
EFFECT OF LOCAL ADMINISTRATION OF HYALURONIC ACID ON ORTHODONTIC TOOTH MOVEMENT IN A RABBIT MODEL
1Department of orthodontics, Faculty of Dentistry, Alexandria University, Egypt
2Department of Orthodontics, Faculty of Dentistry, Alexandria University, Egypt
3Department of Orthodontics, Faculty of Dentistry, Alexandria University, Egypt.
4Professor, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt
Abstract
Introduction: Using a biocompatible material to control tooth movement and enhance anchorage may be a useful method to help the orthodontist to give better treatment results. Objectives: To evaluate the effect of hyaluronic acid (HA) local injection on orthodontic tooth movement. Materials and Methods: The sample size was 15 male New Zealand rabbits. Randomized prospective split mouth trial was conducted on each rabbit. A mesializing force was applied in both sides for 21 days. Group A (control): Saline was injected on day 0. Group B: HA 1% was injected. Tooth movements were measured on 3D models. Histological analysis of alveolar bone modeling was done at the end of the experiment. Results: The quadrant receiving HA showed less amount of tooth movement than that in the control quadrant. Local administration of HA yielded 10% less tooth movement. Histological analysis revealed less resorptive activity in the quadrant receiving HA. Conclusion: There was statistically significant reduction in orthodontic tooth movement magnitude after local HA administration as well as reduction in bone resorptive activity.
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