aboul azm, D., Elshabrawy, S., aboushelib, M., Ali, H., soliman, E. (2022). Characterization and Evaluation of Osseointegration of Modified PEEK Implants Using Nanohydroxyapatite Particles: Laboratory and Experimental Study. Alexandria Dental Journal, 47(1), 134-142. doi: 10.21608/adjalexu.2021.36047.1086
doaa aboul azm; Sonia morsy Elshabrawy; moustafa nabil aboushelib; Hanaa Mohamed Ali; emad aly soliman. "Characterization and Evaluation of Osseointegration of Modified PEEK Implants Using Nanohydroxyapatite Particles: Laboratory and Experimental Study". Alexandria Dental Journal, 47, 1, 2022, 134-142. doi: 10.21608/adjalexu.2021.36047.1086
aboul azm, D., Elshabrawy, S., aboushelib, M., Ali, H., soliman, E. (2022). 'Characterization and Evaluation of Osseointegration of Modified PEEK Implants Using Nanohydroxyapatite Particles: Laboratory and Experimental Study', Alexandria Dental Journal, 47(1), pp. 134-142. doi: 10.21608/adjalexu.2021.36047.1086
aboul azm, D., Elshabrawy, S., aboushelib, M., Ali, H., soliman, E. Characterization and Evaluation of Osseointegration of Modified PEEK Implants Using Nanohydroxyapatite Particles: Laboratory and Experimental Study. Alexandria Dental Journal, 2022; 47(1): 134-142. doi: 10.21608/adjalexu.2021.36047.1086
Characterization and Evaluation of Osseointegration of Modified PEEK Implants Using Nanohydroxyapatite Particles: Laboratory and Experimental Study
2Dental Biomaterials Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt
3dental biomaterials department alexandria university
4Professor, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt
5Department of Polymeric Materials Research, City of Scientific Research and Technology Applications, New Borg El-Arab City, Alex. Egypt.
Abstract
Introduction: Polyetherether ketone (PEEK) is a semicrystalline thermoplastic polymer that has been proposed as a substitute for metals in dental implants biomaterials because of its mechanical and biological properties. Objectives: This study was aimed to prepare and characterize PEEK implant materials modified by different methods using nanoparticles of hydroxyapatite to overcome its limited bioactivity. The study also evaluated the ability of the modified PEEK implant to enhance osseointegration in a rabbit model. Methods: Four groups of PEEK specimens were prepared. Group1: specimens were constructed from untreated PEEK (control group), group2: specimens were coated with nanoparticles of hydroxyapatite (nHA) after etching the PEEK surfaces with sulfuric acid (98%) for one minute, group3: specimens were be coated with nanoparticles of hydroxyapatite (nHA) after laser treatment of PEEK surfaces with Nd: YAG laser and group4: specimens were be constructed from melt-blended PEEK powder with nanoparticles of hydroxyapatite (nHA/PEEK). Each of the four groups were characterized by scanning electron microscope (SEM), Energy-dispersive X-ray (EXD), Fourier-transformed infrared spectroscopy (FTIR), X-ray Diffraction (XRD), contact angle measuring device and flexural strength test. The ability of each of the four groups to enhance bone osseointegration was evaluated in a rabbit model, by using histomorphometrical analysis. Results: Data was collected, summarized and statistically analyzed using the suitable methods. Conclusion: PEEK biocompatibility and its chemical inertness can be improved with coating the surface with nano sized HA or mix blended of PEEK with nHA which does not affect its mechanical strength.
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