EFFECT OF COLLAGEN MEMBRANE ON HEALING OF ALVEOLAR BONE IN RATS WITH LIGATURE INDUCED PERIODONTITIS

Document Type : Original Article

Authors

1 Oral biology faculty of dentistry pharos university

2 Oral Biology Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt

3 Professor, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt

Abstract

Background: Alveolar process is thickened bone that encloses sockets of teeth in the jaws holding the teeth. Periodontitis is a prevalent condition in which the gums and deeper periodontal structures become inflamed. Inflammation can extend below gums and alongside teeth roots, initiating damage of supporting bone and periodontal ligament. Bioabsorbable (CM) collagen membranes with guided tissue regeneration (GTR) is usually performed to manage periodontal defects. Oral wounds are treated by of Resorbable collagen membranes (RCMs) xenogeneic or allogeneic origin. They are whether resorbable and non-resorbable to be easily used.
Objective: Evaluating biological impact of collagen membrane on alveolar bone healing with a ligature made periodontitis.
Materials and Methods: Forty-five adult male albino rats were used , each of them weighing 200-250 grams (approximately six months of age) and they were divided into three equal groups: group A; (control group), group B; (induced periodontitis), and group C: (collagen membrane)
at week twelve the animals were sacrificed, and mandibles were dissected and histological sections were prepared for histological and histomorphometric analysis.
Results: After 12 weeks, specimens of group B showed alveolar bone loss, while in collagen membrane group, they indicated relative restoration of alveolar bone. Histomorphometric analysis results revealed that bone percentage per field in periodontitis group was lower than collagen membrane treated group.
Conclusion: Placement of collagen membrane accelerates alveolar bone healing and enhances bone formation in periodontal diseases.

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Alexandria Dental Journal
Volume 47, Issue 1
A (Oral and maxillofacial surgery, oral medicine, periodontology, oral radiology, oral pathology, oral biology)
April 2022
Pages 70-74

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