Eldeeb, D., Hommos, A., Talaab, M., Soliman, S. (2023). HISTOLOGICAL EVALUATION OF ANGELICA SINENSIS IN MANAGEMENT OF CLASS II FURCATION DEFECT (AN EXPERIMENTAL STUDY). Alexandria Dental Journal, 48(3), 62-69. doi: 10.21608/adjalexu.2023.176994.1328
Dina W. Eldeeb; Ahmed Mohamed Hommos; Maha Ramzy Talaab; Samia Soliman. "HISTOLOGICAL EVALUATION OF ANGELICA SINENSIS IN MANAGEMENT OF CLASS II FURCATION DEFECT (AN EXPERIMENTAL STUDY)". Alexandria Dental Journal, 48, 3, 2023, 62-69. doi: 10.21608/adjalexu.2023.176994.1328
Eldeeb, D., Hommos, A., Talaab, M., Soliman, S. (2023). 'HISTOLOGICAL EVALUATION OF ANGELICA SINENSIS IN MANAGEMENT OF CLASS II FURCATION DEFECT (AN EXPERIMENTAL STUDY)', Alexandria Dental Journal, 48(3), pp. 62-69. doi: 10.21608/adjalexu.2023.176994.1328
Eldeeb, D., Hommos, A., Talaab, M., Soliman, S. HISTOLOGICAL EVALUATION OF ANGELICA SINENSIS IN MANAGEMENT OF CLASS II FURCATION DEFECT (AN EXPERIMENTAL STUDY). Alexandria Dental Journal, 2023; 48(3): 62-69. doi: 10.21608/adjalexu.2023.176994.1328
HISTOLOGICAL EVALUATION OF ANGELICA SINENSIS IN MANAGEMENT OF CLASS II FURCATION DEFECT (AN EXPERIMENTAL STUDY)
1periodontology, faculty of dentistry, Alexandria university , Egypt
2Professor, Department of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dentistry, Alexandria University
3Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology Department , Faculty of dentistry , Alexandria university
4Professor, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt
Abstract
Introduction: proper management of furcation involvements has always been a demanding issue in periodontal therapy. Herbal medicine is nowadays proposed to provide novel alternative approaches for restoring defective bone. A Chinese herb known as Angelica sinensis (As) has various pharmacological effects as it promotes proliferation and differentiation of osteoblasts Objectives: The aim of this study was to evaluate the effectiveness of Angelica sinensis in conjunction with β-tricalcium phosphate in the management of class II furcation defects in dogs Materials and Methods: This randomized study was carried on 6 clinically healthy mongrel dogs. 24 grade II critical-sized furcation defects were surgically created in the mandibular third and fourth premolars. 12 defects were filled with Beta-tricalcium phosphate (β-TCP) bone graft only (control group). While in the other 12 defects β-TCP was mixed with Angelica sinensis powder (experimental group). The defects were covered by collagen membrane, The dogs were sacrificed at 4 and 8 weeks postoperative. Results: The histological analysis has revealed better regenerative features regarding alveolar bone, periodontal ligament and cementum in the experimental groups when compared to control groups. Conclusions: Angelica sinensis herb could enhance the periodontal regenerative potential of β-TCP bone graft.
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