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Alexandria Dental Journal
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Volume Volume 50 (2025)
Volume Volume 49 (2024)
Issue Issue 3
A (Oral and maxillofacial surgery, oral medicine, periodontology, oral radiology, oral pathology, oral biology)
Issue Issue 3
B (Endodontics, Prosthodontics, Fixed prosthodontics, Conservative dentistry, Dental Biomaterials)
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Issue Issue 2
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A (Oral and maxillofacial surgery, oral medicine, periodontology, oral radiology, oral pathology, oral biology)
Issue Issue 1
B (Endodontics, Prosthodontics, Fixed prosthodontics, Conservative dentistry, Dental Biomaterials)
Issue Issue 1
C (Pediatric dentistry, Dental public health, Orthodontics)
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Hassaan, M., Rashad, N., El Sawa, A., Sedik, A. (2024). EFFICACY OF HYDROXYAPATITE NANOPARTICLES IN DENTINAL TUBULE OCCLUSION AND RESISTANCE TO EROSIVE WEAR (SCANNING ELECTRON MICROSCOPIC STUDY). Alexandria Dental Journal, 49(1), 57-65. doi: 10.21608/adjalexu.2023.211107.1379
Mayar Hassaan; Nagah Rashad; Afaf El Sawa; Aya Sedik. "EFFICACY OF HYDROXYAPATITE NANOPARTICLES IN DENTINAL TUBULE OCCLUSION AND RESISTANCE TO EROSIVE WEAR (SCANNING ELECTRON MICROSCOPIC STUDY)". Alexandria Dental Journal, 49, 1, 2024, 57-65. doi: 10.21608/adjalexu.2023.211107.1379
Hassaan, M., Rashad, N., El Sawa, A., Sedik, A. (2024). 'EFFICACY OF HYDROXYAPATITE NANOPARTICLES IN DENTINAL TUBULE OCCLUSION AND RESISTANCE TO EROSIVE WEAR (SCANNING ELECTRON MICROSCOPIC STUDY)', Alexandria Dental Journal, 49(1), pp. 57-65. doi: 10.21608/adjalexu.2023.211107.1379
Hassaan, M., Rashad, N., El Sawa, A., Sedik, A. EFFICACY OF HYDROXYAPATITE NANOPARTICLES IN DENTINAL TUBULE OCCLUSION AND RESISTANCE TO EROSIVE WEAR (SCANNING ELECTRON MICROSCOPIC STUDY). Alexandria Dental Journal, 2024; 49(1): 57-65. doi: 10.21608/adjalexu.2023.211107.1379

EFFICACY OF HYDROXYAPATITE NANOPARTICLES IN DENTINAL TUBULE OCCLUSION AND RESISTANCE TO EROSIVE WEAR (SCANNING ELECTRON MICROSCOPIC STUDY)

Article 15, Volume 49, Issue 1, April 2024, Page 57-65  XML PDF (426.92 K)
Document Type: Original Article
DOI: 10.21608/adjalexu.2023.211107.1379
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Authors
Mayar Hassaan email 1; Nagah Rashad2; Afaf El Sawa3; Aya Sedikorcid 4
1Demonstrator of Oral Biology, Faculty of Dentistry, Arab Academy for Science, Technology & Maritime Transport, Egypt.
2Professor of Oral Biology, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt.
3Professor, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Egypt
4Lecturer of Oral Biology, Department of Oral Biology, Faculty of Dentistry, Alexandria University, Alexandria, Egypt
Abstract
Introduction: Dentin hypersensitivity (DH) is a major dental problem that is manifested as sharp pain of short duration. The cause of DH is controversial; however, the most accepted theory is the hydrodynamic theory. Attempts were made for the treatment of DH as fluoride containing-toothpastes and mouthwashes. Recently, it was found that nanoparticles maybe used for the treatment of DH as they are biocompatible and bioactive materials.
Objectives: To investigate the efficacy of hydroxyapatite nanoparticles in occluding dentinal tubules and resisting erosive wear.
Methodology: Twenty-seven teeth, extracted for orthodontic purpose were used in the present study to obtain 27 dentin discs. Dentin discs were prepared by slicing the teeth from the mid-coronal part. Dentin discs were etched with 37% orthophosphoric acid for 20 seconds then washed with distilled water for 1 minute. Afterwards, they were randomly divided into 2 groups: Group I (Etched control), Group II (Hydroxyapatite nanoparticles): the etched dentin discs were treated with hydroxyapatite nanoparticles. After 7 days, Group II was divided into 2 subgroups; subgroup A: stored in artificial saliva and subgroup B: subjected to erosive challenge by 0.3% citric acid. Finally, dentin discs were analyzed by scanning electron microscope (SEM) and energy dispersive x-ray (EDX).
Results: Group II-A showed more occluded dentinal tubules compared to group I and group II-B. The results of the EDX showed increase in calcium and phosphorous percentage in Group II-A than groups I and II-B.
Conclusion: Hydroxyapatite nanoparticles may be a promising treatment for dentin hypersensitivity.

Keywords: dentin hypersensitivity, hydroxyapatite nanoparticles, dentin.
Keywords
dentin hypersensitivity; hydroxyapatite nanoparticles; dentin
Main Subjects
Oral biology
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