dawood, R., hanno, A., Wahba, N., mahmoud, S. (2024). AN IN VITRO EVALUATION OF EROSIVE EFFECT OF SOME COMMONLY PRESCRIBED ANTIBIOTICS ON PRIMARY ENAMEL INTEGRITY. Alexandria Dental Journal, 49(1), 188-194. doi: 10.21608/adjalexu.2024.265307.1472
radwa mohamed dawood; azza hanno; Nadia Wahba; sawsan h mahmoud. "AN IN VITRO EVALUATION OF EROSIVE EFFECT OF SOME COMMONLY PRESCRIBED ANTIBIOTICS ON PRIMARY ENAMEL INTEGRITY". Alexandria Dental Journal, 49, 1, 2024, 188-194. doi: 10.21608/adjalexu.2024.265307.1472
dawood, R., hanno, A., Wahba, N., mahmoud, S. (2024). 'AN IN VITRO EVALUATION OF EROSIVE EFFECT OF SOME COMMONLY PRESCRIBED ANTIBIOTICS ON PRIMARY ENAMEL INTEGRITY', Alexandria Dental Journal, 49(1), pp. 188-194. doi: 10.21608/adjalexu.2024.265307.1472
dawood, R., hanno, A., Wahba, N., mahmoud, S. AN IN VITRO EVALUATION OF EROSIVE EFFECT OF SOME COMMONLY PRESCRIBED ANTIBIOTICS ON PRIMARY ENAMEL INTEGRITY. Alexandria Dental Journal, 2024; 49(1): 188-194. doi: 10.21608/adjalexu.2024.265307.1472
AN IN VITRO EVALUATION OF EROSIVE EFFECT OF SOME COMMONLY PRESCRIBED ANTIBIOTICS ON PRIMARY ENAMEL INTEGRITY
1pediatric dentistry and public health department,alexandria university, Alexandria ,egypt
2pediatric dentistry and dental public health department, faculty of dentistry,alexandria university, alexandria,egypt
3Professor, Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Alexandria University, Egypt
4pediatric dentistry and dental public health departmentAlexandria university,faculty of dentisrty,alexandria university, alexandria ,egypt
Abstract
Introduction: Children are frequently subjected to liquid medications, especially antibiotics. They are acidic, have low pH and high titratable acidity. This can erode enamel. Aim: This in vitro study aim to determine the correlation between antibiotics as regards their erosive effect and frequency of intake on primary enamel integrity. Materials and Methods: Three commonly prescribed pediatric antibiotics groups: macrolides, cephalosporins and mixed composition were chosen. pH and titratable acidity of the selected antibiotics and artificial saliva were determined. Seventy seven human primary teeth, exfoliated or extracted for orthodontic reasons were randomly assigned to three antibiotics groups and a control group, 11specimens for each group. Specimens were immersed in fresh solutions of antibiotics for 1 minute over 3, 5and 10 days, depending on the type of antibiotic. All samples were preserved in artificial saliva in between immersion cycles. Enamel micro hardness was evaluated at baseline, 3& 5&10 days. Results: Highest percent reduction was recorded for the mixed antibiotic (24.39 ±4.65) P
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