EFFICIENCY OF CONCENTRATED GROWTH FACTORS ON IMMEDIATE IMPLANT STABILITY AND OSSEOINTEGRATION IN POSTERIOR MANDIBLE (RANDOMIZED CONTROLLED CLINICAL TRIAL)

Document Type : Original Article

Authors

1 BDS, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Egypt.

2 Professor of Oral and Maxillofacial Surgery. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Egypt

3 Lecturer of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Egypt

Abstract

Introduction: Plasma derivatives that include growth factors are shown to hasten osseointegration & boost implant stability. With growth factors it includes, concentrated growth factor (CGF), this can be accomplished.
Objectives: To evaluate both clinically and radiographically efficiency of concentrated growth factors on implant stability and osseointegration in immediately placed dental implants in lower posterior mandible.
Materials and Methods: In lower posterior mandibular area 17 immediate implants were located in study group & a defect of 2 mm or more were filled with CGF, bone graft & covered with collagen membrane, while 17 immediate implants were placed in the control group and bone graft and collagen membrane were used to fill defect without CGF. Clinical evaluation was done to assess implant stability at first and fourth week, pain, edema and presence of infection at first week. Radiographic evaluation for peri implant bone density, peri implant crestal bone loss was also done.
Results: Clinical evaluation included implant stability evaluation, pain and edema. Radiographic evaluation included peri-implant crestal bone loss and a peri-implant bone density evaluation. No statistically significant results had been shown between control and study group according to pain, edema and peri-implant bone loss values. There was highly significant results between study and control group according to peri-implant bone density with higher values according to study group.
Conclusion: Concentrated growth factor speeded implant osseointegration procedure & impacted stability values positively.

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Alexandria Dental Journal
Volume 50, Issue 1
A (Oral and maxillofacial surgery, oral medicine, periodontology, oral radiology, oral pathology, oral biology)
April 2025
Pages 1-8

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