A CLINICOPATHOLOGICAL STUDY OF OROFACIAL SWELLINGS (A PROSPECTIVE STUDY)

Taher, Sarah R.; Hassan, Nagy E.; El Sheikh, Sahar M.; El Dibany, Riham M.

doi:10.21608/adjalexu.2016.58043

A CLINICOPATHOLOGICAL STUDY OF OROFACIAL SWELLINGS (A PROSPECTIVE STUDY)

Document Type : Original Article

Authors

¹ Bachelor of Dentistry, BDS, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.

² Professor of Oral and Maxillofacial surgery, Faculty of Dentistry, Alexandria University, Egypt.

³ Professor of Oral Pathology, Faculty of Dentistry, Alexandria University, Egypt.

10.21608/adjalexu.2016.58043

Abstract

INTRODUCTION: The etiology of orofacial swellings could be attributed to the presence of inflammation, congenital developmental malformations and neoplasia. Orofacial swellings may occur in the nasal cavities, paranasal sinuses, ear, eye, facial skin, oral cavity and salivary glands. Swellings of the orofacial region include cysts and tumors. Cysts are divided into developmental and inflammatory types. Tumors are divided into benign and malignant types. OBJECTIVES: Perform clinicopathological correlation of orofacial swellings and assess the frequency of incidence regarding age, sex, site, and type of lesion. MATERIALS AND METHODS: A clinicopathological prospective study was conducted on 100 patients suffering from swellings in the orofacial region attending the outpatient clinic of the oral and maxillofacial surgery department. The histopathological examination was done. Statistical analysis was carried out on the tabulated data using (IBM SPSS 20.0) software. RESULTS: It was found that the incidence of all swellings in males was slightly more than females. The incidence of all swellings in the second and third decades of age. The mandible was the most frequently affected site. Using the histological classification of the World Health Organization (WHO), 32% were classified as cysts, 26% as odontogenic tumors, 25% as non-odontogenic tumors, 11% fibro-osseous lesions and 6% as salivary gland tumors. CONCLUSIONS: Cysts are the most common oral swellings, followed by odontogenic tumors. The treatment modalities were: marsupialization, enucleation, resection, segmental mandibulectomy and hemimandibulectomy. Following surgical removal of jaw swelling, the entire surgical specimen should be examined histopathologically

Keywords

References

1.RidgeJA,GlissonBS,HorwitzEM,MeyersMO.Head and neck tumors. In:RichardP, KevinAC, Lawrence DW,William JH. 11th ed. Cancer Management: A Multidisciplinary Approach book. United Kingdom: Cmp United Business Media, 2008. 39-89.

2. Thomas G, Hashibe M, Jacob BJ, Ramadas K, Mathew B, Sankaranarayanan R, et al. Risk for Factors Multiple Oral Premalignant Lesions. Int J Cancer 2003; 107: 285-91.
3. Ravi M, Mamata S, Kishore GR, Manish S, Kapoor AK. Trends of prevalence and pathological spectrum of head and neck cancers in North India. Indian J Cancer 2005; 42: 89- 93.
4. Manor E, Kachko L, Puterman MB, Szabo G, Bodner L. Cystic Lesions of the Jaws – A Clinicopathological Study of 322 Cases and Review of the Literature. Int J Med Sci 2012; 9: 20-6.
5. Ghosh PK. Odontogenic and Non-Odontogenic Tumors. Synopsis of Oral and Maxillofacial Surgery book. 1st ed. India: Jaypee Brothers Medical Publishers, 2006. 96-107.
6. Pogrel MA, Schmidt BL, Robertson CG. Clinical Pathology: Odontogenic and Nonodontogenic Tumors of the Jaws. In: Part II oncology book. 2006. 490-534.
7. College of American Pathologists. National Cancer Institute, American Head and Neck Society. squamous cell carcinoma of the lip or oral cavity. 2011.
8. Rousseau A, Badoual C. Atlas of Head and Neck Pathology, Squamous Cell Carcinoma. Genet Cytogenetics Oncol Haematol 2011.
9. Flávia ADO, Eliza CBD, Cláudia TT, Aline AM, Érica Carvalho DA, Rita DCA, et al. Salivary Gland Tumor: A Review of 599 Cases in a Brazilian Population. Head Neck Pathol 2009; 3: 271-5.
10.Riachi F, Tabarani C. Effective Management of Large Radicular Cysts Using Surgical Enucleation vs. Marsupialization. IAJD 2009; 1: 44-51.
11.Caruana SM, Close LG, Rahmati R. Head and Neck Masses. Columbia: Columbia Presbylerian Medical Center, Dep Otolaryngol, Div Head Neck Surg, 2007.
12.Gaspar C, Zapater E, Chust M, et al. Experience in the treatment of 98 carcinomas of the nasopharynx. Long-term follow-up and analysis of prognostic factors. Acta Otorrinolaringol Esp 2000; 51:691-6.
13.Busquets J, Garcia H, Trindad-Pinedo J, et al. Clinicopathologic characteristics of head and neck squamous cell carcinoma in Puerto Ricans. PR Health Sci J 2003; 22:254-64.
14. Mosqueda-Taylor A, Irigoyen-Camacho ME, Diaz- Franco MA, Torres-Tejero MA. Odontogenic cysts. Analysis of 856 cases. Med Oral 2002; 7: 89-96.
15. Ochsenius G, Escobar E, Godoy L, Penãfiel C. Odontogenic cysts: analysis of 2,944 cases in Chile. Med Oral Patol Oral Cir Bucal 2007; 12: E85-91.
16. Ledesma-Montes C, Hernández-Guerrero JC, Garcés-Ortíz M. Clinico-pathologic study of odontogenic cysts in a Mexican sample population. Arch Med Res 2000; 31: 373- 6.
17.Meningaud JP, Oprean N, Pitak-Arnnop P, Bertrand JC. Odontogenic cysts: a clinical study of 695 cases. J Oral Sci 2006; 48: 59-62.
18. Koseoglu BG, Atalay B, Erdem MA. Odontogenic cysts: a clinical study of 90 cases. J Oral Sci 2004; 46: 253-7.
19.Bataineh AB, Rawashdeh MA, Al Qudah MA. The prevalence of inflammatory and developmental odontogenic cysts in a Jordanian population: a clinicopathologic study. Quintessence Int 2004; 35: 815-9.
20. Tay AB. A 5-year survey of oral biopsies in an oral surgical
unit in Singapore: 1993-1997. Ann Acad Med Singapore
1999; 28: 665-71.
21. Shear M. Cysts of the oral regions. 3rd ed. London: Wright,
Oxford, 1992. 75-98.
22. Waldron CA. Odontogenic cysts and tumors. In: Neville B,
Damm D, Allen C, Bouquot J (eds). Oral & maxillofacial
pathology, Philadelphia: WB Saunders, 1995. 481-524.
23. Elarbi M, El-Gehani R, Subhashraj K, Orafi M. Orofacial tumors in Libyan children and adolescents. A descriptive study of 213 cases. Int J Pediatr Otorhinolaryngol 2009; 73:
237-42.
24. Tanaka N, Murata A, Yamaguchi A, Kohama G. Clinical
features and management of oral and maxillofacial tumors in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88: 11-5.
25. Ulmasky M, Lustmann J, Balkin N. Tumors and tumor-like lesions of oral cavity and related structures in Israeli children. Int J Oral Maxillofac Surg 1999; 28: 291-4.
26. Adebayo ET, Ajike SO, Adekeye EO. Tumors and tumor- like lesions of the oral and perioral structures of Nigerian children. Int J Oral Maxillofac Surg 2001; 30: 205-8.
27. Al-Khateeb TH, Ababneh KT. Salivary tumors in north Jordanians: a descriptive study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103: e53–e9.
28. Otoh EC, Johnson NW, Olasoji H, Danfillo IS, Adeleke OA. Salivary gland neoplasms in Maiduguri, north-eastern Nigeria. Oral Dis 2005; 11: 386-91.
29. Kayembe MK, Kalengayi MM. Salivary gland tumors in Congo (Zaire). Odontostomatol Trop 2002; 25: 19-22.
30. Ansari MH. Salivary gland tumors in an Iranian population: a retrospective study of 130 cases. J Oral Maxillofac Surg 2007; 65: 2187-94.