Negm, S., Lotfy, M., Soliman, S., Sadek, A. (2021). HISTOMORPHEMITC EVALUATION OF THE EFFICACY OF AMNIOTIC CHORION MEMBRANE IN MANAGEMENT OF GRADE II FURCATION DEFECTS (IN VITRO STUDY). Alexandria Dental Journal, 46(Issue 2), 39-44. doi: 10.21608/adjalexu.2020.88456
Shady Negm; Mona Lotfy; Samia Soliman; Ali Sadek. "HISTOMORPHEMITC EVALUATION OF THE EFFICACY OF AMNIOTIC CHORION MEMBRANE IN MANAGEMENT OF GRADE II FURCATION DEFECTS (IN VITRO STUDY)". Alexandria Dental Journal, 46, Issue 2, 2021, 39-44. doi: 10.21608/adjalexu.2020.88456
Negm, S., Lotfy, M., Soliman, S., Sadek, A. (2021). 'HISTOMORPHEMITC EVALUATION OF THE EFFICACY OF AMNIOTIC CHORION MEMBRANE IN MANAGEMENT OF GRADE II FURCATION DEFECTS (IN VITRO STUDY)', Alexandria Dental Journal, 46(Issue 2), pp. 39-44. doi: 10.21608/adjalexu.2020.88456
Negm, S., Lotfy, M., Soliman, S., Sadek, A. HISTOMORPHEMITC EVALUATION OF THE EFFICACY OF AMNIOTIC CHORION MEMBRANE IN MANAGEMENT OF GRADE II FURCATION DEFECTS (IN VITRO STUDY). Alexandria Dental Journal, 2021; 46(Issue 2): 39-44. doi: 10.21608/adjalexu.2020.88456
HISTOMORPHEMITC EVALUATION OF THE EFFICACY OF AMNIOTIC CHORION MEMBRANE IN MANAGEMENT OF GRADE II FURCATION DEFECTS (IN VITRO STUDY)
1BDS, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.
2Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
3Professor of Oral Biology, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
4Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Abstract
Introduction: Treatment of furcation defects especially critical size defects remains a considerable challenge in clinical practice. Treatment modalities vary according to the type and location of the defects. Regenerative procedures are one of the treatment modalities in furcation involvement. Objectives: The aim of this study was to evaluate histomorphometrically the regenerative potential of amnion chorion membrane (ACM) on the management of induced grade II furcation defects and compare it to collagen membrane. Material and methods: This study was conducted on eight adult male Mongrel dogs, about 18-24 months old, weighing approximately 18-24 Kgs. On the left sides; the created defects were filled with β-tricalcium phosphate + hydroxy apatite and covered by amnion chorion membrane (study group). While on the right sides; the created defects were filled with the β-tricalcium phosphate + hydroxyapatite then covered by collagen membranes (control group). Results: ACM has shown superior results in bone formation when compared to control group treated with resorbable collagen membrane. Conclusion: ACM is an effective, easy to handle, safe, and time saving membrane that can be used in periodontal regeneration and management of grade II furcation defects.
2. Sims T, Takei HH. Furcation involvement and treatment. In: Newman MG, Takei HH. Klokkevold PR, Carranza FA (eds). Caranza's Clinical Periodontology. 12th ed. Philadelphia: Elsevier Saunders; p 621-7.
3. American Academy of Periodontology. Parameter on occlusal traumatism in patients with chronic periodontitis. J Periodontol. 2000;71(Suppl5):873-5.
4. Shenoy VK, Rodrigues S. Iatrogenic dentistry and the periodontium. J Indian Prosthodont Soc. 2007;7:17-20.
5. Graetz C, Plaumann A, Wiebe JF, Springer C, Salzers, Dorfer CE. Periodontal probing versus radiographs for diagnosis of furcation involvement. J Periodontol. 2014;85:1371-9.
6. Pradeep AR, Priyanka N, Kalra N, Naik SB, Singh SP, Martande S. Clinical efficacy of subgingivally delivered 1.2 mg simvastatin in the treatment of individuals with Class II furcation defects: a randomized controlled clinical trial. J Periodontol. 2012; 83:1472-3.
7. Jepsen S, Eberhard J, Hernera D, Needlenem T. A systematic review of guided tissue regeneration for periodontal furcation defects. What is the effect of guided tissue regeneration compared with surgical debridement in the treatment of furcation defects? J Clin Periodontol. 2002;29(Suppl3):103-16,160-2.
8. Gamal AY, lacono VJ. Enhancing guided tissue regeneration of periodontal defects by using a novel perforated barrier membrane. J Periodontol. 2013;84:905-13.
9. Wang HL, Cooke J. Periodontal regeneration techniques for treatment of periodontal diseases.Dent Clin North Am. 2005;49:637-59.
10. Santan RB, Leite de Mattos GM, Dyke TV. Efficacy of combined regenerative treatments in human mandibular class II furcation defects. J Periodontol. 2009;80:1756-64.
11. Gianobelle WV, Rayan S, Shih MS, Su DL, Kaplan PL, Chan TCK. Recombinant human osteogenic protein-1(OP-1) stimulates periodontal wound healing in class III furcation defects. J Periodontol. 1998;69:129-37.
12. Rosen P. A Case Report on Combination Therapy Using a Composite Allograft Containing Mesenchymal Cells With an Amnion-Chorion Barrier to Treat a Mandibular Class III Furcation. Clin Adv Periodontics 2013;2:64-69.
13. Gupta A, Kedige S, Jain k. Amnion and chorion membranes: potential stem cell reservoir with wide applications in periodontics. Int J Biomater. 2015;2015:1-9.
14. Pakkala T, Virtanen I, Oksanen J, Jones C, Hormia M. Function of laminins and laminin binding integrins in gingival epithelial cell adhesion. J Periodontol. 2002;73:709-19.
15. Glickman I. Clinical Periodontology 4th ed. Philadelphia: WB Saunders Co; 1964. p 203-5.
16. Daniel W. Biostatistics: A foundation for analysis in the health science .6th ed. NY: John Wiley and sons, Inc; 1995.
17. Paul S, Stuart J, Cohen D. Consecutive case series using a composite allograft containing mesenchymal cells with an amnion chorion barriers to treat mandibular class III/IV furcations. IJPR 2015;35:453-60.
18. Tarnow D, Flecher P. Classification of vertical component of furcation involvement. J Periodontol. 1984;55:283-4.
19. Glavind L, Loe H. Error in the clinical assessment of periodontal destruction. J Periodont Res. 1967;2:180.
20. Bourque WT, Gross M, Hall BK. A histological processing technique that preserves the integrity of calcified tissues (bone, enamel), yolky amphibian embryos, and growth factor antigens in skeletal tissue. J Histochem Cytochem 1993;41:1429- 34.Kotz S, Balakrishnan N, Read CB, Vidakovic B. Encyclopedia of statistical sciences. 2nd ed. Hoboken, NJ: Wiley-Interscience; 2006.
21. Kirkpatrick LA, Feeney BC. A simple guide to IBM SPSS statistics for version 20.0. Student ed. Belmont, Calif: Wadsworth, Cengage Learning; 2013.
22. Leonhardt A, Dahlen G, Envert S. Five-year clinical, microbiological and radiological outcome following treatment of peri-implantitis in man. J Periodontol. 2003;74:1415-22.
23. Patel RA, Wilson RF, Palmer RM. The Effect of Smoking on Periodontal Bone Regeneration: A Systematic Review and Meta-Analysis. J Periodontol. 2012;83:143-55.
24. Manfredini D, Poggio CE, Lobbezoo F. Is bruxism a risk factor for dental implants? A systemic review of the literature. Clin Implant Dent Relat Res. 2012;16:460-9.
25. Dastoor SF, Travan S, Wang HL. Effect of Adjunctive Systemic Azithromycin With Periodontal Surgery in the Treatment of Chronic Periodontitis in Smokers: A Pilot Study. J Periodontol. 2007;78:1887-96.
26. Misch KA, Yi ES, Sarment DP. Accuracy of Cone Beam Computed Tomography for Periodontal Defect Measurements. J Periodontol 2006;77:1261-66.
27. Angelopoulos C, Thomas S, Hechler S, Parisis N, Hlavacek M. Comparison Between Digital Panoramic Radiography and Cone-Beam Computed Tomography for the Identification of the Mandibular Canal as Part of Presurgical Dental Implant Assessment. J Oral Maxillofac Surg. 2008;66:2130-5.
28. Holtzclaw D, Toscano N. Amnion chorion allograft barrier: Indications and techniques update. JIACD. 2012;4:25-38
29. Koizumi NJ, Inatomi TJ, Sotozono CJ, Fullwood NJ, Quantock AJ, Kinoshita S. Growthfactor m RNA and protein in preserved human amniotic membrane. Curr Eye Res. 2000;20:173-7.
30. Shimmura S, Shimazaki J, Ohashi Y, Tsubota K. Antiinflammatory effects of amniotic membrane transplantation in ocular surface disorders. Cornea. 2001;20:408-13.
31. Gupta I, Gupta R, Gokhale ST, Sharma A. Placental tissues: fixing smiles. Int J Innov Scientific Res 2014;7:57-62.
32. Sali DD, George JP. Demineralized Freeze Dried Bone Allograft With Amniotic Membrane in the Treatment of Periodontal Intrabony Defects - 12 Month Randomized Controlled Clinical Trial. J Periodontol. 2016;10:1-18
33. Holtzclaw D, Hinze HF, Toscano N. Gingival flap attachment healing with amnionchorion allograft membrane: A controlled, split mouth case report replication of the classic 1968 Hiatt Study. J Implant Adv Clin Dent. 2012;4:19-25.
34. Holtzclaw DJ, Toscano NJ. Amnion–chorion allograft barrier used for guided tissue regeneration treatment of periodontal intrabony defects: A retrospective observational report. Clin Adv Periodontics. 2013;3:131-7.
35. Rosen PS. A Case Report on Combination Therapy Using a Composite Allograft Containing Mesenchymal Cells With an Amnion–Chorion Barrier to Treat a Mandibular Class III Furcation. Clin Adv Periodontics. 2013;3:64-69.
36. Kumar A, Chandra RV, Reddy AA, Reddy BH, Reddy C, Naveen A. Evaluation of clinical, antiinflammatory and antiinfective properties of amniotic membrane used for guided tissue regeneration: A randomized controlled trial. Dent Res J (Isfahan). 2015; 12:127-35.
37. In ‘t Anker PS, Scherjon SA, Kleijburg-van der Keur C, de Groot-Swings GM, Claas FH, Fibbe WE, et al. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells. 2004;22:1338-45.
38. Gomes JA, Romano A, Santos MS, Dua HS. Amniotic membrane use in ophthalmology. Curr Opin Ophthalmol. 2005;16:233-40.
39. Kothiwale SV, Anuroopa P, Gajiwala AL. A clinical and radiological evaluation of DFDBA with amniotic membrane versus bovine derived xenograft with amniotic membrane in human periodontal grade II furcation defects. Cell Tissue Bank 2009;10:317-26.
40. Gamal, R. M., Lotfy, M., & Taalab, M. (2018). Evaluation of the efficacy of amniotic chorion membrane in management of grade ii furcation defects. Alexandria Dental Journal, 43, 102-108.
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