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Sager, M., Darwish, S., Melek, L. (2015). THE EFFECT OF BIOSCAFFOLD ALVELAC™ IN PRESERVATION OF ALVEOLAR BONE AFTER EXTRACTION OF TEETH (CLINICAL AND RADIOGRAPHIC STUDY). Alexandria Dental Journal, 40(1), 22-26. doi: 10.21608/adjalexu.2015.58729
M Sager; S Darwish; L Melek. "THE EFFECT OF BIOSCAFFOLD ALVELAC™ IN PRESERVATION OF ALVEOLAR BONE AFTER EXTRACTION OF TEETH (CLINICAL AND RADIOGRAPHIC STUDY)". Alexandria Dental Journal, 40, 1, 2015, 22-26. doi: 10.21608/adjalexu.2015.58729
Sager, M., Darwish, S., Melek, L. (2015). 'THE EFFECT OF BIOSCAFFOLD ALVELAC™ IN PRESERVATION OF ALVEOLAR BONE AFTER EXTRACTION OF TEETH (CLINICAL AND RADIOGRAPHIC STUDY)', Alexandria Dental Journal, 40(1), pp. 22-26. doi: 10.21608/adjalexu.2015.58729
Sager, M., Darwish, S., Melek, L. THE EFFECT OF BIOSCAFFOLD ALVELAC™ IN PRESERVATION OF ALVEOLAR BONE AFTER EXTRACTION OF TEETH (CLINICAL AND RADIOGRAPHIC STUDY). Alexandria Dental Journal, 2015; 40(1): 22-26. doi: 10.21608/adjalexu.2015.58729

THE EFFECT OF BIOSCAFFOLD ALVELAC™ IN PRESERVATION OF ALVEOLAR BONE AFTER EXTRACTION OF TEETH (CLINICAL AND RADIOGRAPHIC STUDY)

Article 4, Volume 40, Issue 1, July 2015, Page 22-26  XML PDF (412.41 K)
Document Type: Original Article
DOI: 10.21608/adjalexu.2015.58729
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Authors
M Sager1; S Darwish2; L Melek3
1B.D.S.Faculty of Dentistry, Tripoli University
2Professor of Oral & Maxillofacial Surgery, Faculty of Dentistry, Alexandria University
3- Lecturer of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University
Abstract
Introduction: After tooth extraction, the extraction socket heals by forming a blood clot which leads to the formation of new bone within 3-4 months. Although bone deposition in the socket will continue for several months, it will not reach the crestal level of the neighboring teeth. Objective: Is to clinically and radiographically evaluate the use of Bioscaffold Alvelac™ in preservation of dimensional measure of alveolar bone after extraction of teeth. Materials and methods: This study was conducted on twelve patients divided in to two equal groups (study group and control group). Indicated for extraction of anterior maxillary teeth, in the study group, the bioscaffold Alvelac™ was inserted into the empty socket after extraction and was supported by 3-0 silk with figure of eight sutures. In the control group, extraction of upper anterior teeth was done without introducing any material and the wound was sutured. Results: There was a statistically significant decrease of alveolar bone width and height in both groups at three months postoperative interval compared with the bone width and height at the immediate postoperative period. Conclusion: Immediate tooth extraction stabilizes the bioscaffold Alvelac™ material in the socket and allows it to act as a scaffold for bone deposition. From this study, it is clear that, this material allows preservation of the dimensional measure of the alveolar bone.
Keywords
Tooth extraction; alveolar bone; Socket preservation; Scaffold; Alvelac™
References
1. Browser G, Chadroff B, Carnevale R. Histologic evaluation of new attachment apparatus in human. Part П. J Periodontol 1989; 60: 675-82.
2. Kruger H. The book of oral and maxillofacial surgery. 1st ed. Missouri: Mosby, 1984. 231.
3. Lubin CT, Lanyon LE. Osteoregulatory nature of mechanical stimuli: function as a determinant for adaptive remodelling in bone. J Orthop Res 1987; 5: 300-10.
4. Pagni G, Pellegrini G, Giannobile WV, Rasperini G. Postextraction alveolar ridge preservation: biological basis and treatments. Int J Dent 2012; 2012: 151030.

5. Misch CM, Misch CE. The repair of localized severe ridge defects for implant placement using mandibular bone grafts. Implant Dent 1995; 4: 261- 7.
6. Truhlar RS, Orenstein IH, Morris HF, Ochi S. Distribution of bone quality in patients receiving endosseous dental implants. J Oral Maxillofac Surg 1997; 55: 38-45.
7. Lustmann J, Lewinstein I. Interpositional bone grafting technique to widen narrow maxillary ridge. Int J Oral Maxillofac Implants 1995; 10: 568-77.
8. Ashman A. Post extraction ridge preservation using synthetic alloplast. Implant Dent 2000; 9: 168-76
9. Ashman A, Rosenlicht J. Ridge preservation
addressing a major problem in dentistry. Dent Today
1993; 12: 80-4.
10. Araújo MG, Lindhe J. Dimensional ridge
alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol 2005; 32: 212-8.
11. Chandrasekeran M, Lau S, Gunaseelan R, Prabhu V. Rapid technique to evaluate human bone quality using novel Micro CT with histology resolution. Bone 2009; 44(Suppl 2): S268.
12. Boyne PJ. Osseous repair of the postextraction alveolus in man. Oral Surg Oral Med Oral Pathol 1966; 21: 805-13.
13. Hsieh YD, Devlin H, Roberts C. Early alveolar ridge osteogenesis following tooth extraction in the rat. Arch Oral Biol 1994; 39: 425-8.
14. Devlin H, Sloan P. Early bone healing events in the human extraction socket Int J Oral Maxillofac Surg 2002; 31: 641-5.
15. Min C, Wikesjo U, Park J, Chae G, Pippig S, Bastone P, et al. Wound healing/regeneration using recombinant human growth/differentiation factor-5 in an injectable poly-lactide-co-glycolide-acid composite carrier and a one-wall intra-bony defect model in dogs. J Clin Periodontol 2011; 38: 261–8.
16. Makadia H, Siegel S. Poly Lactic-co-Glycolic Acid (PLGA) as a biodegradable controlled drug delivery carrier. Polymers 2011; 3: 1377–97.
17. Shen H, Hu X, Yang F, Bei J, Wang S. An injectable scaffold: rhBMP-2-loaded poly(lactide- co-glycolide) / hydroxyapatite composite microspheres. Acta Biomater 2010; 6: 455-65.
18. McKay W, Peckham S, Badura J. A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft). Int Orthop 2007; 31: 729–34.
19. Brown A, Zaky S, Ray H Jr, Sfeir C. Porous magnesium/PLGA composite scaffolds for enhanced bone regeneration following tooth extraction. Acta Biomater 2015; 11: 543-53.
20. Mikos AG, Thorsen A, Czerwonka L, Bao Y, Langer R, Winslow D, et al. Preparation and
characterization of poly (l-lactic acid) foams. Polymer 1994; 35-77.
21. Wang HL, Kiyonobu K, Neiva RF. Socket augmentation: rationale and technique. Implant dentistry 2004; 13: 286-96.
22. Fickl S, Zuhr O, Wachtel H, Bolz W, Huerzeler M. Hard tissue alterations after socket preservation: an experimental study in the beagle dog. Clin Oral Implant Res 2008; 19: 1111–8.
23. Sethi A, KausT. Maxillary ridge expansion with simultaneous implant placement: a 5-year results of an ongoing clinical study. Int J Oral Maxillofac Implants 2000; 15: 491-9.
24. Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Molecular pharmaceutics 2008; 5: 487-95.
25. Serino G, Rao W, Iezzi G, Piattelli A. Polylactide and polyglycolide sponge used in human extraction sockets: bone formation following 3 months after its application. Clin Oral Implant Res 2008;19(1):16– 31.
26. Fan V. Sacaffold to aid tooth implants. NUH 2008; 26: 1-2.
27. Araujo AC, Mendes VC, Junior OF, Carvalho PS, Guan L, Davies JE. Investigation of a Novel PLGA/CaP Scaffold in the Healing of Tooth Extraction Sockets to Alveolar Bone Preservation in Humans. Clin Implant Dent Relat Res 2015; 5: 1-12.
28. Serino G, Biancu S, Iezzi G, Piattelli A. Ridge preservation following tooth extraction using a polylactide and polyglycolide sponge as space filler: a clinical and histological study in humans. Clin Oral Implant Res 2003; 14: 651-8.

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